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Soft-tissue tumors

Spindle cell / pleomorphic lipoma

Soft tissueBenignAdipocytic tumours

Epidemiology

A benign variant of lipoma, classically found on the shoulder, chest wall, or back of adult men. Its superficial location on the shoulder, chest wall, or back helps recognize it and avoid confusing it with liposarcoma.

Basic features

It may feel more solid than a common lipoma, but its clinical and histological features are benign; unlike an atypical lipomatous tumor (which shows MDM2 amplification), it usually expresses CD34 and shows loss of RB1, which confirms its benign nature.

Usual treatment

It is resected if it is symptomatic, grows, or raises diagnostic doubt about an atypical adipocytic tumor.

Outcomes and prognosis

The outcome is very favorable and no metastasis is expected.

This information is general and does not replace a medical evaluation. A musculoskeletal tumor must be interpreted together with imaging, physical examination, biopsy when appropriate and each patient's context.

Specialist evaluation

If you have a mass, a bone lesion or a report suggesting a tumor, book an evaluation.

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