Dr. Francisco Bengoa
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Soft-tissue tumors

Myxofibrosarcoma

Soft tissueMalignant / sarcomaFibroblastic / myofibroblastic tumours

Epidemiology

A sarcoma that is common in older adults, especially in the limbs. Its microscopic spread along superficial planes can be greater than the lump you can feel, which is why assessment and planning with a preoperative MRI is essential.

Basic features

It grows in an infiltrative, tail-like pattern along the fascial planes, which can make it difficult to obtain negative margins.

Usual treatment

It is treated with surgery involving wide resection, and radiotherapy in many cases, planning the resection in detail with an MRI. Chemotherapy is reserved for highly selected high-risk cases; its role is not fully defined for all patients with this tumor.

Outcomes and prognosis

The overall prognosis is intermediate. Local recurrence is common and may precede higher-grade disease.

Warning signs

These signs do not necessarily mean cancer, but they warrant evaluation before operating on or needling a mass.

  • A soft-tissue mass that grows, is larger than 5 cm, or is deep.
  • Persistent, night-time or progressive bone pain, especially if it limits activity.
  • A fracture from minimal trauma, or an aggressive bone lesion on an X-ray.
  • A lump that comes back after previous surgery.
  • Neurological symptoms, rapid swelling, or pain associated with a mass.

This information is general and does not replace a medical evaluation. A musculoskeletal tumor must be interpreted together with imaging, physical examination, biopsy when appropriate and each patient's context.

Specialist evaluation

If you have a mass, a bone lesion or a report suggesting a tumor, book an evaluation.

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