Dr. Francisco Bengoa
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Bone tumors

Low-grade central osteosarcoma

BoneMalignant / sarcomaOsteogenic tumours

Epidemiology

An uncommon subtype of osteosarcoma, generally in young adults, that can look like a benign fibrous lesion. It can mimic fibrous dysplasia, so correlating the biopsy with imaging avoids inadequate curettage.

Basic features

It grows more slowly than conventional osteosarcoma but is still malignant and can dedifferentiate.

Usual treatment

Wide resection with adequate margins is essential; chemotherapy is not always used when pure low grade is confirmed.

Outcomes and prognosis

With complete resection the prognosis is very favorable, but it worsens if there is dedifferentiation or incomplete resection.

Warning signs

These signs do not necessarily mean cancer, but they warrant evaluation before operating on or needling a mass.

  • A soft-tissue mass that grows, is larger than 5 cm, or is deep.
  • Persistent, night-time or progressive bone pain, especially if it limits activity.
  • A fracture from minimal trauma, or an aggressive bone lesion on an X-ray.
  • A lump that comes back after previous surgery.
  • Neurological symptoms, rapid swelling, or pain associated with a mass.

This information is general and does not replace a medical evaluation. A musculoskeletal tumor must be interpreted together with imaging, physical examination, biopsy when appropriate and each patient's context.

Specialist evaluation

If you have a mass, a bone lesion or a report suggesting a tumor, book an evaluation.

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