Epidemiology
A rare benign tumor of perineurial cells, arising in a nerve or in soft tissue. It can present within a nerve with a progressive deficit, so the neurological examination guides the plan.
Basic features
It can present as a slow-growing mass or as a progressive neuropathy, depending on whether it involves a major nerve. Unlike schwannoma, its cells express EMA and not S100, which helps confirm it.
Usual treatment
Resection is individualized because removing an intraneural lesion can affect function.
Outcomes and prognosis
It usually follows a benign course, with the main goal being to preserve neurological function.