Epidemiology
It mainly affects middle-aged and older adults; it can arise from smooth muscle or blood vessels. Its relationship to the blood vessels changes how the surgery is planned.
Basic features
It can appear in the limbs, pelvis, or chest wall; the grade, depth, and site modify the risk.
Usual treatment
Wide resection when possible, radiotherapy in selected settings, and systemic treatment if there is advanced disease.
Outcomes and prognosis
It carries a risk of metastasis, especially to the lungs and liver. In soft-tissue leiomyosarcomas of the limb, the prognosis depends mainly on the grade and the size; follow-up aims to detect recurrence early.
